Not excluding the impact of environmental influences, “wisdom might even be a personality trait that could be roughly 35 to 50 percent genetically inherited”, he contends. “The prefrontal cortex, hands-down, is the most important part of the neurobiology of wisdom,” Jeste was quoted in the Washington Post. “Located behind the forehead, the prefrontal cortex is the newest part of the brain evolutionarily.”
This poses the fundamental question: What is wisdom?
Across many cultures and centuries, he’s found that wise people are compassionate and empathetic, aware of their gifts and blind spots, open-minded, resolute and calm amid uncertainty, altruistic decision-makers who learn from their experiences, able to see from many perspectives and ‘altitudes’ and often blessed with a sense of adventure and humor.
Know Thyself 